John Isner is set to defend his ATP Winston Salem title but the North Carolina native will face some stiff competition from Jo-Wilfried Tsonga and Tomas Berdych.
Isner grew up in nearby Greensboro and he was a very popular champion last year, receiving plenty of vociferous support which helped him through a succession of tight matches.
"It means a lot for sure to win," he said after beating Julien Benneteau in three sets in the 2011 final. "Any time you win a tournament at this level, it is a huge accomplishment. For me personally, it is great, to win here in virtually my hometown. I think this is perfect preparation for me heading up north."
Isner will be among the favourites again after some sublime tennis on the North American hard courts this summer. He won the Newport title, made the semis in Atlanta and reached the semi-finals again at the Toronto Masters.
However with two other top ten players in the draw this year, things are going to be tough. World number six Jo-Wilfried Tsonga is the favourite for the title having made the semis of Wimbledon back in July and world number seven Tomas Berdych has been given a wildcard. Berdych has filled his summer so far with a series of early exits but with the amount of power in his game, you can never count him out on this surface.