Americans Mardy Fish, Sam Querrey and John Isner lead the field for the Delray Beach International Tennis Championships this week.
Andy Roddick may have withdrawn after capturing his 30th career title in Memphis at the weekend but there is still plenty of home interest.
Fish is second seed in Delray Beach. The American had a slow start to the year but he found form in Memphis, making the semi-finals before getting gunned down by the hottest prospect on tour right now, Milos Raonic.
However while Fish should be in the running for the title, do not expect too much of a strong challenge from Querrey and Isner. Querrey in particular has disappointed since picking up four titles in the first half of last season. The Californian's progress has stalled and he lost first round in Sydney, Melbourne and San Jose.
Del Potro has made back to back semi-finals on the North American hard courts and the former US Open champion looks certain to return to the top of the game very soon. He's probably the smart pick to take the title this week.
Kevin Anderson picked up the SA Open title in Johannesburg this week but the South African is in a very strong quarter which also contains Del Potro and Isner.